June 25, 2023

Estriol: Uses, Side Effects, Dosage, and Interactions

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Written by Thy TranHoang

estriol uses and side effects

What is Estrogen Therapy

Estrogen therapy is a form of hormone replacement therapy used to relieve menopause symptoms that may be caused by reduced production of estrogen. Estriol is one of three types of estrogen. In this article we estriol’s uses and side effects.

Compared to the other two types, estriol is considered to have the weakest estrogen-like effect. This means that there will be fewer side effects when used in hormone replacement therapy compared to stronger other forms of estrogen. 

Estriol and Perimenopause Symptom Relief

During menopause, about 40% to 45% of women experience vagina dryness and vagina infections due to reduced production of estrogen. Low doses of estriol combined with probiotic can help reduce vagina dryness and risks of vagina infections.

Studies have shown that 2 milligrams of estriol per day can help ease hot flashes, night sweats, and insomnia in menopausal women. Estriol can also strengthen bone density and help reduce high blood pressure in menopausal women.

While estriol pills are considered safe to take, estriol patches or topical cream are more ideal for long term uses. Several studies have shown that abnormal or heavy postmenopausal bleeding are more common among women who take estriol pills compared to women who use topical estriol cream for the same period of time. 

Estriol and FDA Approval

Although estriol can be considered the next generation of estrogen therapy, it is not FDA-approved. Estriol is considered to be a bioidentical hormone that has not been proven to be safe nor effective by the FDA.

In addition, drugs that contain estriol are considered to be compounded drugs that are not reviewed by the FDA for effectiveness, safety, and quality standards.  

Food/Drug: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

At It’sFetch.co we strive to provide valuable and reliable health information through our blog. We believe in empowering individuals to make informed decisions about their health and well-being. However, it is important to understand that the content on our blog is not intended to replace the advice, diagnosis, or treatment provided by a qualified medical professional. 

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